Curriculum Vitae

Current Positions and Leadership

• Since 2019: Full Professor, Sorbonne University, Paris, France.
• Since 2019: Principal Investigator, Paris Brain Institute, Paris, France.
• 2023–2027: Elected member of the Inria Evaluation Committee.
• Since 2020: Advisory Board member, European Society of Digital and Integrative Pathology.

Major Scientific Responsibilities

• 2018–2022: Member of the Board of Directors of the MICCAI Society.
• MICCAI 2020: General Chair, Lima, Peru.
• 2018–2020: President, European Society of Digital and Integrative Pathology.
• 2016–2018: Vice-President, European Society of Digital and Integrative Pathology.
• 2008–2014: Director of the CNRS International Research Lab IPAL, UMI CNRS 2955, Singapore.

Professional Experience

• 2016–2018: Full Professor, Pontificia Universidad Católica del Perú, Lima, Peru.
• 2011–2016: Full Professor, University Pierre and Marie Curie, Paris, France.
• 2013–2015: Adjunct Full Professor, National University of Singapore.
• 2011–2013: CNRS Senior Research Fellow, IPAL, Singapore.
• 2009–2013: Adjunct Associate Professor, National University of Singapore.
• 2005–2011: CNRS Research Fellow, IPAL, Singapore.
• 1999–2005: Associate Professor, University Marie & Louis Pasteur, and Research Fellow, FEMTO-ST Institute, CNRS UMR 6174, Besançon, France.
• 1998–1999: Project Manager, General Electric Energy European Technology Center, Belfort, France.
• 1997–1998: Logistics and Planning Manager, Gaussin S.A., Héricourt, France.
• 1993–1996: Lecturer, Institute of Technology Nord Franche-Comté, University Marie & Louis Pasteur, Belfort, France.
• 1992–1993: Research Fellow, R&D Institute for Welding and Material Testing, ISIM, Timișoara, Romania.

Scientific Activities

My research focuses on high-content biomedical image analysis, integrative computational pathology, omics imaging, spatial transcriptomics, multimodal biomedical AI and responsible artificial intelligence. The central goal is to design AI methods that connect tissue morphology, molecular information and clinical interpretation in a trustworthy and clinically meaningful way.

Main Recent Projects

• SIMAI: Synergizing Mechanistic and AI Approaches for Modeling the Impact of Microenvironment Heterogeneity on Immunotherapy Efficacy, MIC 2025 grant, 2025–2029.
• STRATIFIAD: Refining Alzheimer Disease Patients’ stratification using effective, traceable and explicable AI in computational histopathology, Big Brain Theory grant, Paris Brain Institute, 2021–2023.
• MALMO: Mathematical Approaches to Modelling Metabolic Plasticity and Heterogeneity in Melanoma, AVIESAN / ITMO Cancer grant, 2020–2023.
• PAPHOS: Platform for Advanced Prescriptive Health Operational System, EIT Health grant, 2016–2018.
• FlexMIm: Collaborative digital histopathology, FUI grant, French Ministry of Industry, 2013–2016.

International Research Leadership: IPAL Singapore

From 2005 to 2014, my research at IPAL UMI CNRS focused on biomedical image analysis, semantic medical image indexing, medical image retrieval, multimodal fusion, medical ontologies and knowledge-based reasoning for medical image interpretation.

Main Projects

• MICO: Cognitive Microscope, ANR TecSan program, 2011–2014.
• EURO-TELEPATH: Telepathology Network in Europe, COST Action, 2007–2011.
• IVS4NSC: Intelligent Vision System for Quantitative Microscopy in Neural Stem Cells, A*STAR/JCO, 2009–2013.
• MMedWeb: Multimedia Medical Conceptual Web for Intelligent Information Access, A*STAR/SERC, 2007–2010.
• ONCO-MEDIA: Ontology and Context Related Medical Image Distributed Intelligent Access, ICT-ASIA Programme, 2006–2010.

Selected Events Co-organized

• ICPR 2014 — Mitosis & Atypia International Benchmark, Stockholm, Sweden.
• ICPR 2012 — Mitosis Detection International Benchmark, Tsukuba, Japan.
• SinFra 2012 — Singaporean-French IPAL Symposium, Paris.
• WCCI 2010 — IEEE World Congress on Computational Intelligence, special session on image understanding and visual cognition.
• SFBI 2011 — Singaporean-French BioImaging Seminar, Biopolis, Singapore.

Earlier Research: FEMTO-ST

At FEMTO-ST, my teaching and research focused on artificial intelligence for dynamic monitoring, diagnosis, prognosis, maintenance, e-maintenance, fault detection, real-time systems, nonlinear systems and discrete event systems.

Main Projects

• PROTEUS: Generic platform for e-maintenance, FP5 European Integrated Project, ITEA programme.
• NEMOSYS: Naval E-Maintenance Oriented System, industry-funded project involving French industrial and academic partners.

Industrial Experience

• General Electric Energy European Technology Center: Project Manager, gas turbine department, Belfort, France, 1998–1999. Design, technical, production, logistics and financial management of gas turbine projects.
• Gaussin S.A.: Logistics and Planning Manager, Héricourt, France, 1997–1998. Logistics, supply chain management and distributed subsidiary structure management.
• Institute of Technology Nord Franche-Comté: Lecturer, 1993–1996. Teaching in logistics management, supply chain management and flexible production systems.

Academic Background

• 2006: HDR, Control and Computer Sciences, University Marie & Louis Pasteur, Besançon, France. HDR manuscript · HDR synopsis · HDR slides.
• 1997: Ph.D., Control and Computer Sciences, University Marie & Louis Pasteur, Besançon, France, with highest distinction. Manuscript · PhD slides.
• 1993: M.Sc., Control Sciences, Université de Technologie de Belfort-Montbéliard, France, with distinction.
• 1992: M.Eng. / Dipl.Ing., Mechatronic Production Systems, Politehnica University of Timișoara, Romania, with highest distinction.